Sertaconazole nitrate shows fungicidal and fungistatic activities against Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, causative agents of tinea pedis.
نویسندگان
چکیده
The fungistatic and fungicidal activities of sertaconazole against dermatophytes were evaluated by testing 150 clinical isolates of causative agents of tinea pedis, Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum. The overall geometric means for fungistatic and fungicidal activities of sertaconazole against these isolates were 0.26 and 2.26 μg/ml, respectively, although values were higher for T. mentagrophytes than for the others. This is the first comprehensive demonstration of the fungicidal activity of sertaconazole against dermatophytes.
منابع مشابه
The Achilles Project Prevalence of Tinea Pedis and Onychomycosis in Malta
Tinea pedis (athlete’s foot) is a common fungal infection of the feet with the major causative organisms being Trichophyton rubrum, Trichophyton mentagrophytes and Epidermophyton floccosum1. It occurs worldwide, with a greater frequency and severity during the warmer months of the year. The condition is most prevalent in adult men, especially in the presence of excessive perspiration and occlus...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 55 9 شماره
صفحات -
تاریخ انتشار 2011